Abstract
Left ventricular assist device (LVAD)associated infections represent a major complication during long-term support. Additionally, during prolonged antibiotic treatment, antimicrobial resistance and adverse effects may occur. Therefore, alternative anti-bacterial approaches should be evaluated. We report about the successful treatment of two patients with chronic recurrent LVAD pump-associated infections after local application of bacteriophages as adjunct to standard surgical and antimicrobial treatment. No side effects occurred. At the follow up visits six/nine months later the surgical sites showed no signs of infection. Our experience justifies further investigation into the indication and the therapeutic success of bacteriophages in LVAD-associated infections.
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