TREATMENT OF CARDIOVASCULAR SYPHILIS WITH PENICILLIN

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Article1 December 1946TREATMENT OF CARDIOVASCULAR SYPHILIS WITH PENICILLINHENRY I. RUSSEK, M.D., F.A.C.P., JOHN C. CUTLER, M.D., STEPHEN A. FROMER, M.D., BURTON L. ZOHMAN, M.D., F.A.C.P.HENRY I. RUSSEK, M.D., F.A.C.P.Search for more papers by this author, JOHN C. CUTLER, M.D.Search for more papers by this author, STEPHEN A. FROMER, M.D.Search for more papers by this author, BURTON L. ZOHMAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-25-6-957 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMost authorities agree that specific therapy in cardiovascular syphilis favorably influences the course of the disease and increases life expectancy.1 According to Scott2 "any medication that tends to allay the process in the aorta and thus prevent its spread to the aortic orifice or retard the development of aneurysm, may add years to the patient's life." Moore and his associates,3 using preparatory heavy metals to avoid the possibility of Herxheimer reaction, followed by conservative arsenotherapy, have reported striking effects on the mortality rate and the average duration of life in this form of the disease.The demonstration by Mahoney, Arnold...Bibliography1. WHITE PD: Heart disease, 1944, ed. 3, The MacMillan Company, New York, p. 385. Google Scholar2 SCOTT RW: in Oxford Medicine, The Oxford University Press, New York, 1942, p. 508. Google Scholar3. MOOREDANGLADESREISINGER JEJHJC: Treatment of cardiovascular syphilis: Results obtained in fifty-three patients with aortic aneurysm and in 112 with aortic regurgitation, Arch. Int. Med., 1932, xlix, 879. PADGET, P., MOORE J. E.: The results of treatment in cardiovascular syphilis: A report of three years' additional observation, Am. Heart Jr., 1935, x, 1017. CrossrefGoogle Scholar4. MAHONEYARNOLDHARRIS JFDCA: Penicillin treatment of early syphilis: A preliminary report, Ven. Dis. Inform., 1943, xxiv, 355. Google Scholar5. WILE UJ: News from the centers, Bull. Rapid Treatment Centers, 1945, ii, 12. Google Scholar6. DOLKARTSCHWEMLEIN REGX: The treatment of cardiovascular syphilis with penicillin, Jr. Am. Med. Assoc., 1945, cxxix, 515. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication April 27, 1946.From the Cardiovascular Research Division and Venereal Disease Research Laboratory of the U. S. Marine Hospital, Staten Island, New York.Published with the permission of the Surgeon General, U. S. Public Health Service, Washington, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byKrankheiten der GefäßeCardiovascular Syphilis: A CLINICAL STUDY OF 578 CASESPenicillin Treatment of Cardiovascular SyphilisThe Specific Treatment of Syphilitic AortitisPenicillin Treatment of Patients with Cardiovascular Syphilis in Congestive FailureZweite wissenschaftliche SitzungPenicillin therapy of cardiovascular syphilisFatal Jarish-Herxheimer Reaction with Sudden Aneurysmal Dilatation and Complete Bronchial Occlusion Following Penicillin TherapySyphilis 1 December 1946Volume 25, Issue 6Page: 957-959KeywordsCardiovascular therapyDeath ratesHeavy metalsLife expectancyMedical servicesPenicillinResearch laboratoriesSexually transmitted diseasesSurgeonsSyphilis Issue Published: 1 December 1946 PDF downloadLoading ...