Abstract

Topicality: Inflammation of the adenoid tonsil is one of the common causes of ENT diseases in children. Among the causes of adenoiditis (nasopharyngitis) are infectious - viral and bacterial, allergic and gastric acid irritation in laryngopharyngeal reflux. The aim of our research was to study the effectiveness of topical application of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% in the treatment of pediatric patients with pharyngeal tonsillitis. Materials and methods: We selected 60 patients aged 5 to 14 years with endoscopically confirmed adenoid vegetations of I-II stage with inflammation. Patients were divided into 2 groups – main and control. Patients in the control group received saline irrigation therapy 4 times a day, patients in the main group received saline lavage 4 times a day and intranasal administration of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% three times a day for 7 days. Patient status was analyzed using a Likert scale questionnaire and objective endoscopic examination. Results: During treatment, a positive effect was observed in both groups. However, starting from the second visit (on the 3rd day of treatment) there was a faster decrease in symptoms in children of the main group compared to the control, on the 7th day the difference between the groups was subjective – 5.9 points, and objective – 2.5 points in favor of the main group. Therefore, intranasal administration of a combination of xylometazoline hydrochloride 0.05% and miramistin 0.01% helps reduce edema, redness, exudation, improves nasal breathing and in combination with saline irrigation therapy is an effective means for topical treatment of children with inflammatory diseases of the pharynx.

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