Abstract

PurposeThe aim of the present study was to explore the efficacy and safety of transurethral needle electrode resection and transurethral holmium laser resection of non-muscular invasive bladder cancer (NMIBC).Patients and methodsIn this prospective, case-control study, patients from the Urinary Surgery or Oncology Department who met the inclusion and exclusion criteria received transurethral needle electrode resection (n = 52) or transurethral holmium laser resection (n = 51).ResultsA total of 103 patients with NMIBC were included in the present study, with 68 males and 35 females. Their mean age was 57.3 years. Sixty-two patients had Ta, 15 patients had T1, and 26 patients had Tis. Operative time, intraoperative blood loss, postoperative gross hematuria time, bladder irrigation time, and postoperative hospitalization time were all significantly lower in the transurethral holmium laser resection group than the transurethral needle electrode resection group. After resection, transurethral holmium laser resection significantly decreased the value of HGF, TSH, and TNF-α versus the transurethral needle electrode resection group. The incidence of obturator reflex was significantly lower in the transurethral holmium laser resection group than the transurethral needle electrode resection group. There was no significant difference in disease-free survival rate and progression-free survival rate between the two groups.ConclusionsTransurethral holmium laser resection has clinical advantages in the treatment of NMIBC.

Highlights

  • Bladder cancer is a common malignancy of the urinary system, and its incidence ranks 9th in the world, 6th in men, and 10th in women

  • We aimed to explore the efficacy of transurethral needle electrode resection and transurethral holmium laser resection for non-muscular invasive bladder cancer (NMIBC) based on a prospective case-control study and to provide a basis for the selection of clinical treatment

  • This study aimed to explore the efficacy of transurethral needle electrode resection and transurethral holmium laser resection for Non-muscular invasive bladder cancer (NMIBC)

Read more

Summary

Introduction

Bladder cancer is a common malignancy of the urinary system, and its incidence ranks 9th in the world, 6th in men, and 10th in women. The ratio of male to female incidence is 3:1. According to a 2018 epidemiological report, there were about 78,100 new cases of bladder cancer in China (including about 60,600 cases of male, 17,500 of female), and the incidence is 5.71/10 (8.65/10 of male, 2.62/10 of female). Zhou et al World Journal of Surgical Oncology (2020) 18:166 surgical methods of NMIBC include transurethral resection of bladder tumor, photodynamic therapy, transurethral laser surgery, partial cystectomy, and radical cystectomy (RC). There is substantial evidence that RC is still the most commonly used treatment for high-risk NMIBC or patients who develop muscle-layer infiltration [4, 5]

Objectives
Methods
Results
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call