Clinical analysis of transurethral holmium laser therapy for non-muscle invasive bladder cancer

Abstract

Objective To evaluate the advantages and disadvantages of holmium laser resection and transurethral resection for the treatment of non-muscle invasive bladder cancer(NMIBC). Methods The clinical records of totally 167 patients with NMIBC were divided into transurethral holmium laser resection of bladder cancer(HOLRBT) group(n=78) and TURBT group(n=89). The operation time, obturator nerve reflex, the rate of intraoperative bladder perforation, the incidence of postoperative bleeding and the rate of tumor recurrence were compared between the two groups. Results The mean operation time was similar in the two groups (P>0.05). Less obturator nerve reflex, the rate of intraoperative bladder perforation and the incidence of postoperative bleeding were observed in HOLRBT group(P 0.05). Conclusions The HOLRBT therapy has definite effects on the treatment of NMIBT as TURBT.Compared with the TURBT, HOLRBT has more advantages with wieldy operation method, high security and low complication. In short, we should choose the suitable operation means according to the different conditions. Key words: Urinary Bladder Neoplasms; Cystectomy; Lasers, Solid-State; Holmium