Abstract
Dengue Dengue virus genetic variation and ambient temperature influence the rate of transmission by mosquitoes and thus the risk and magnitude of an outbreak. Virus in a blood meal within the vector mosquito's gut takes several days—roughly a quarter of the short life of an Aedes mosquito—to transition from the gut to the salivary gland, ready for inoculation into the next host. So, 1 day's difference can mean success or failure for ongoing transmission. Fontaine et al. found that eight strains of recently circulating dengue virus have different gut–salivary gland transit times. In an agent-based model, this parameter translated into a roughly 20% difference in the probability of a subsequent human infection, with a Haitian strain being the slowest, resulting in smaller outbreaks. PLOS Pathog. 10.1371/journal.ppat.1007187 (2018).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
