Transient elastography with focused shear wave beams

Abstract

Transient elastography (TE) is a clinically available ultrasound elastography technique in which mechanical vibration of a small piston at the tissue surface generates a short shear wave pulse that propagates into the body. The piston doubles as an ultrasonic transducer; thus, the shear wave propagation is measured with pulse-echo ultrasound along the beam axis, yielding the wave speed and tissue stiffness. The long shear wavelength compared to piston diameter used in current devices results in low shear wave signal that decays rapidly on axis as the shear wave spreads in all directions, thus limiting the signal-to-noise ratio and imaging depth in practice. We present an overview of our new technology of focused shear wave beams, which aims to overcome these limitations by concentrating shear wave energy in TE near to the beam axis with vibration of a concave circular piston. Analytical modeling of focused shear wave generation and propagation is validated against measurements in gelatin phantoms. Results indicate that focused shear wave beams have relatively larger amplitudes and penetration depths compared to unfocused shear wave beams. Ongoing modeling and experimental efforts towards the measurement of elastic anisotropy, such as of skeletal muscle, using focused shear wave beams will be discussed.