Abstract
Transient elastography (TE) is used in clinical screenings for liver fibrosis. TE generates shear wave motion in the liver by vibration of a piston at the skin. The small, flat piston in current devices radiates shear waves that diverge from the liver, resulting in low SNR and high failure rates, especially in obese patients. Our group recently introduced focused shear wave beams for TE [Cormack et al., IEEE TBME (2024)], in which vibration of a concave piston generates shear waves that converge towards the focal region, thereby increasing SNR for liver stiffness estimation. However, because piston sizes needed for efficient shear wave focusing are larger than the typical intercostal space, the rib cage that lies between the skin and the liver may cause shear wave aberration and influence stiffness measurement. Here, we present measurements of broadband focused shear wave propagation in tissue-mimicking gel in which are embedded 3D printed human ribs. Both straight elliptical rods and anatomically realistic 3D printed ribs are used as aberrators. Measurements are compared to 3D simulations of shear wave beam propagation [Archer et al., JASA (2023)]. Effects of shear wave aberration by the rib cage depend on shear wavelength, piston-to-rib distance, and piston radius and curvature.
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