Abstract
Abstract Schistosomiasis remains the most important tropical snail-borne trematodiasis that threatens many millions of human lives. In achieving schistosomiasis elimination targets, sustainable control of the snail vectors represents a logical approach. Nonetheless, the ineffectiveness of the present snail control interventions emphasizes the need to develop new complementary strategies to ensure more effective control outcomes. Accordingly, the use of genetic techniques aimed at driving resistance traits into natural vector populations has been put forward as a promising tool for integrated snail control. The use of CRISPR/Cas9 based snail modification strategy appears fascinating and potentially effective. However, this approach is currently still underdeveloped in snail molecular research. This review provides knowledge related to this genetic technique without neglecting the current existing gaps and trying to identify ways to bypass potential future challenges, all are requisites for achieving this promising snail control strategy.
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