Abstract

Transgenerational epigenetic inheritance studies suggest that environmental stress can have lasting effects across generations. It proposes the hypothesis that the expression changes of miRNA-212/132 induced by environmental stress will lead to transgenerational epigenetic inheritance. The validity of this hypothesis is demonstrated through experimental behavior changes, RNA expression differences, nucleotide change experiments, and qRT-PCR analysis, and the influence of environmental stress between generations is confirmed again. This will facilitate the application of relevant practical aspects in the future.

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