Abstract
Transfusion-related acute lung injury (TRALI) is a known cause of transfusion-related morbidity and mortality. TRALI occurs during or within 6 hours of transfusion with clinical features that include respiratory distress, pulmonary oedema and hypoxaemia. This case report will be followed by a discussion that will include general pathophysiology and clinical features of TRALI. The diagnosis is considered to be under-reported. Potential clues available to the pathologist will be discussed, specifically in relation to autopsy. The diagnosis of TRALI is a significant one, as donors of implicated blood products can be identified with the prevention of further potential transfusion reactions.
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