Abstract
ObjectiveTranscultural adaptation and validation of the FACT-C questionnaire to Serbian language.MethodsThe study included 131 patients with colorectal cancer. Translation included standard forward and backward translation from original language to Serbian and back. Pilot testing of the questionnaire was conducted on 10 patients with diagnosed colorectal cancer. The questionnaires EORTC-QLQ-C30 and DASS will be used as validated tools to evaluate validity of examined, FACT-C questionnaire.ResultsThe FACT-C demonstrated satisfactory construct validity using Cronbach’s alpha. Satisfactory concurrent validity was demonstrated using correlations with EORTC-QLQ-C30 and DASS questionnaires. High reproducibility was demonstrated using repeated questionnaires on 30 patients two weeks after the first interview.ConclusionThe Serbian version of the FACT-C was demonstrated to have satisfactory applicability, reliability and validity in Serbian patients with colorectal cancer. It can be considered as a valid colorectal cancer specific health related quality of life tool for the Serbian population.
Highlights
Colorectal cancer (CRC) represents the second leading cause of cancer deaths worldwide [1]
CRC has multiple impacts on health-related quality of life (HRQoL) caused by its symptoms and the consequence of the treatment. It may result in psychophysical or functional impairment or disruption of social and family interactions or can cause a long-lasting depressive mood which can influence on low HRQoL [6]
This module is not validated in Serbian, so in our investigation we used the EORTC-QLQ-C30
Summary
Colorectal cancer (CRC) represents the second leading cause of cancer deaths worldwide [1]. The highest incidence rates are in Australia and New Zealand, Europe, and North America, and the lowest rates are found in Africa and South-Central Asia [1]. It is the third leading cause of cancer death among adults younger than age 50, second among men and the fourth among women in the USA [2, 3]. CRC has multiple impacts on health-related quality of life (HRQoL) caused by its symptoms and the consequence of the treatment. It may result in psychophysical or functional impairment or disruption of social and family interactions or can cause a long-lasting depressive mood which can influence on low HRQoL [6]
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