Transcriptome assessment of healthy highrisk stocker cattle defines mechanisms of inflammatory regulation induced by tulathromycin metaphylaxis

Abstract

Tulathromycin is commonly used as metaphylaxis to reduce bovine respiratory disease (BRD) risk. Current secondary phar­macodynamics characteristics of tulathromycin on the host are poorly understood. RNA Sequencing (RNA-Seq) techniques were used to measure gene expression in healthy cattle admin­istered tulathromycin to elucidate the genomic mechanisms over time.