Traditional transbronchial needle aspiration biopsy in the diagnosis of primary lung cancer in the use of value in the primary hospital

Abstract

Objective To investigate traditional transbronchial needle aspiration biopsy (C-TBNA) using the diagnostic value of lung cancer in primary hospital. Methods The clinical data of patients with 118 cases of primary lung cancer was analyzed retrospectively and the respiratory department of the First Hospital of Jiaxing from January 2013 to December 2014 period was analyzed by C-TBNA pathologic diagnosis, including the lymph nodes and lung tumor puncture biopsy.Meanwhile, all patients did chest CT. Results By means of the positive C-TBNA pathologic analysis among the 118 cases of patients, it gets the result of 45 cases of adenocarcinoma (38.1%), squamous cell carcinoma and 28 cases (23.7%), small cell carcinoma in 17 patients (14.4%). Combining the TNBA lymph nodes and the chest CT comparison, C-TBNA lymph node biopsy in the diagnosis and staging of lung cancer was found significantly better than the chest CT.It can reduce the false negative rate of the chest CT lymph nodes.The positive rate of C-TBNA lymph nodes 1is regardless of the puncture area.118 patients made 289 parts by lymph node biopsy specimens, including 194 positive samples which are divided into three regions (the mediastinum and lower mediastinal region, 10-14 region). Comparing the three groups’region rates, no statistical significant difference was found (P=0.407). All patients was well tolerated, no complications. Conclusion As hilus pulmonis and mediastinal lymph nodes and lung tumor pathology assessment tools, C-TBNA can significantly improve the diagnostic yield of lung cancer.In addition, the positive rate is regardless of the puncture puncture area.The application of bronchoscopy of lung cancer diagnosed is safe, effective and feasible. Key words: Lung neoplasms; Lymph nodes; Biopsy, needle; Tomography, X-ray computed