Abstract
We have traced the mossy fiber projections of the dentate gyrus of the rat and mouse using a new anatomical procedure involving horseradish peroxidase histochemistry. Granule cells take up injected horseradish peroxidase and transport it to their dendrites and axon terminals. As shown by this method, the mossy fibers project in a very narrow septo-temporal plane at right angles to the longitudinal axis of the hippocampus. In addition, discrete loci of the dentate gyrus project to nearly the entire length of the regio inferior. We also consider the detailed organization of the mossy fiber system and the value of horseradish peroxidase histochemistry as a neuroanatomical tool.
Published Version
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