Abstract
Induced-fit responsive dopamine (DA) imprinted polymer, poly (melamine-co-chloranil), was used as a suitable coating material for the modification of a hanging mercury drop electrode. The zwitterionic conformation of the imprinted polymer responded differential pulse, cathodic stripping voltammetric current, without any false-positive or false-negative contributions of non-specific sorptions, in aqueous environment of complex matrices. The limit of detection (3 σ) of dopamine was found to be as low as 0.148 ng mL −1, by the proposed sensor that could be considered a sensitive marker of dopamine depletion in Parkinson's disease (PD).
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