TRABECULAR JUVENILE OSSIFYING FIBROMA OF THE MANDIBLE: A CASE REPORT

Abstract

This report aims to describe an extensive fibro-osseous lesion in a 24-year-old woman with an enlargement in the left mandible. Computed tomography showed a large multiloculated hypodense area between teeth 36 and 42, with thinning and expansion of cortical bone. Under the clinical hypothesis of central giant cell lesion, preoperative exams and incisional biopsy were performed, which was conclusive for a fibro-osseous lesion. The lesion was resected, and the mandibular reconstruction was performed with a titanium plate. Histopathologic analysis of the excised specimen showed fusocellular proliferation with trabecular deposition of immature bone and osteoid, among numerous multinucleated giant cells. Additionally, cavities filled with red blood cells and supported by cellularized fibrous connective tissue were observed. The anatomopathologic conclusion of the surgical specimen was a benign fibro-osseous lesion, leading to the diagnosis of trabecular juvenile ossifying fibroma associated with aneurysmal bone cyst. The patient is in follow-up. This report aims to describe an extensive fibro-osseous lesion in a 24-year-old woman with an enlargement in the left mandible. Computed tomography showed a large multiloculated hypodense area between teeth 36 and 42, with thinning and expansion of cortical bone. Under the clinical hypothesis of central giant cell lesion, preoperative exams and incisional biopsy were performed, which was conclusive for a fibro-osseous lesion. The lesion was resected, and the mandibular reconstruction was performed with a titanium plate. Histopathologic analysis of the excised specimen showed fusocellular proliferation with trabecular deposition of immature bone and osteoid, among numerous multinucleated giant cells. Additionally, cavities filled with red blood cells and supported by cellularized fibrous connective tissue were observed. The anatomopathologic conclusion of the surgical specimen was a benign fibro-osseous lesion, leading to the diagnosis of trabecular juvenile ossifying fibroma associated with aneurysmal bone cyst. The patient is in follow-up.