JUVENILE AGGRESSIVE OSSIFYING FIBROMA WITH ANEURISMATIC BONE CYST AREAS: REPORT OF TWO CASES

Abstract

Juvenile ossifying fibroma (JOF) is a benign fibro-osseous lesion that commonly affects gnathic bones. It has a predilection for the maxilla of young individuals. Occasionally, it may be associated with other pathologic entities such as aneurysmal bone cyst (ABC), which may lead to a more aggressive behavior of the lesion. Here, we report 2 cases of expansive, rapidly growing intraosseous lesions, located in the maxilla region, both affecting young males aged 11 and 12 years. Computed tomography showed well-defined osteolytic lesions, with hypodense/hyperdense areas and cortical bone expansion. Enucleation and complete curettage of the lesions were performed. In both cases, the anatomopathologic diagnosis of aggressive JOF associated with ABC was rendered. After follow-up of about 3 and 6 years, no relapse has been observed. Juvenile ossifying fibroma (JOF) is a benign fibro-osseous lesion that commonly affects gnathic bones. It has a predilection for the maxilla of young individuals. Occasionally, it may be associated with other pathologic entities such as aneurysmal bone cyst (ABC), which may lead to a more aggressive behavior of the lesion. Here, we report 2 cases of expansive, rapidly growing intraosseous lesions, located in the maxilla region, both affecting young males aged 11 and 12 years. Computed tomography showed well-defined osteolytic lesions, with hypodense/hyperdense areas and cortical bone expansion. Enucleation and complete curettage of the lesions were performed. In both cases, the anatomopathologic diagnosis of aggressive JOF associated with ABC was rendered. After follow-up of about 3 and 6 years, no relapse has been observed.