Abstract

BackgroundExplaining policy change is one of the central tasks of contemporary policy analysis. In this article, we examine the changes in infection control policies for multi-drug resistant tuberculosis (MDR-TB) in South Africa from the time the country made the transition to democracy in 1994, until 2015. We focus on MDR-TB infection control and refer to decentralised management as a form of infection control. Using Kingdon’s theoretical framework of policy streams, we explore the temporal ordering of policy framework changes. We also consider the role of research in motivating policy changes.MethodsPolicy documents addressing MDR-TB in South Africa over the period 1994 to 2014 were extracted. Literature on MDR-TB infection control in South Africa was extracted from PubMed using key search terms. The documents were analysed to identify the changes that occurred and the factors driving them.ResultsDuring the period under study, five different policy frameworks were implemented. The policies were meant to address the overwhelming challenge of MDR-TB in South Africa, contextualised by high prevalence of HIV infection, that threatened to undermine public health programmes and the success of antiretroviral therapy rollouts. Policy changes in MDR-TB infection control were supported by research evidence and driven by the high incidence and complexity of the disease, increasing levels of dissatisfaction among patients, challenges of physical, human and financial resources in public hospitals, and the ideologies of the political leadership. Activists and people living with HIV played an important role in highlighting the importance of MDR-TB as well as exerting pressure on policymakers, while the mass media drew public attention to infection control as both a cause of and a solution to MDR-TB.ConclusionThe critical factors for policy change for infection control of MDR-TB in South Africa were rooted in the socioeconomic and political environment, were supported by extensive research, and can be framed using Kingdon’s policy streams approach as an interplay of the problem of the disease, political forces that prevailed and alternative proposals.

Highlights

  • Explaining policy change is one of the central tasks of contemporary policy analysis

  • The need for policy change was reinforced by the outbreak of XDRTB in KwaZulu-Natal from 2005 to 2006, which served as a serious warning that gains made in the treatment of TB could be lost if infection prevention and control (IPC) measures for multi-drug resistant tuberculosis (MDR-TB) were not effectively and rapidly addressed [17]

  • Prevention of MDR-TB was considered a priority for MDRTB control, given the need to limit the spread of the disease and considering the high cost, toxicity and poor treatment outcomes with available therapies

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Summary

Introduction

Explaining policy change is one of the central tasks of contemporary policy analysis. We examine the changes in infection control policies for multi-drug resistant tuberculosis (MDR-TB) in South Africa from the time the country made the transition to democracy in 1994, until 2015. According to a report published by the Department of Health [6], approximately 450,000 new cases of TB occurred in South Africa in 2013, including more than 26,000 cases of MDR-TB. This is burdensome as MDRTB is extremely expensive to treat, requiring ZAR 25,000–30,000 per patient for the drugs alone as opposed to less than ZAR 200 for a new patient with ordinary TB [7]. MDR-TB infection control remains one of the major cornerstones underpinning TB management programmes [15, 16]

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