Toward Bridging Unmet Medical Need in Early Alzheimer's Disease: An Evaluation of Beta-Amyloid (Aβ) Plaque Burden as a Potential Drug Development Tool.

Hao Zhu,Mehul Mehta,Shiew‐Mei Huang,Yaning Wang

doi:10.1002/cpt.2536

Toward Bridging Unmet Medical Need in Early Alzheimer's Disease: An Evaluation of Beta-Amyloid (Aβ) Plaque Burden as a Potential Drug Development Tool.

Hao Zhu, Mehul Mehta + Show 2 more

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https://doi.org/10.1002/cpt.2536

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Journal: Clinical Pharmacology & Therapeutics	Publication Date: Feb 20, 2022
Citations: 13	License type: CC BY-NC 4.0

Affiliation: Center for Drug Evaluation and Research, United States Food and Drug Administration

#Aβ Plaque Burden #Clinical Dementia Rating Scale–sum Of Boxes #Aβ Plaque #Late-phase Trials #Standard End Point #Aβ Plaque Levels #anti-Aβ Antibodies #Alzheimer’s Disease #Group-level Change #Drug Development Tools

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Toward Bridging Unmet Medical Need in Early Alzheimer's Disease: An Evaluation of Beta-Amyloid (Aβ) Plaque Burden as a Potential Drug Development Tool.