Abstract

BackgroundIn an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA). However, the impact of tourniquet use on transfusion rate and postoperative length of stay (PLOS) in TKA remains controversial. Therefore, we carried out a study to investigate the effect of tourniquet application in routine primary TKA on transfusion rate and PLOS.MethodsWe analyzed data from 6325 patients who underwent primary unilateral TKA and divided them into two groups according to whether a tourniquet was applied during the procedure, and a tourniquet was used in 4902 and not used in 1423. The information for transfusion and PLOS was extracted from patients’ electronic health records, and the data were analyzed with logistic and linear regression analyses.ResultsFollowing TKA, the transfusion rate and PLOS were 14.52% and 7.72 ± 3.54 days, respectively, in the tourniquet group, and 6.47% and 6.44 ± 3.48 days, respectively, in the no-tourniquet group. After adjusting for the different related variables, tourniquet use was significantly correlated with a higher transfusion rate (risk ratio = 1.888, 95% confidence interval (CI) 1.449–2.461, P < 0.001) and a longer PLOS (partial regression coefficient (B) = 0.923, 95%CI 0.690–1.156, P < 0.001).ConclusionsOur findings suggested that tourniquet use in routine primary TKA was related to a higher transfusion rate and a longer PLOS. The impact of tourniquet use on transfusion rate and PLOS should be taken into account in clinical practice.

Highlights

  • In an enhanced recovery after surgery program, a growing number of orthopedists are reconsidering the necessity of tourniquet use in total knee arthroplasty (TKA)

  • Opponents of tourniquets propose that their use in TKA can lead to skin blistering, soft-tissue damage, muscle atrophy, ischemia–reperfusion injury, hematoma at the thigh, and weakness of the quadriceps; tourniquet use can hamper early mobilization and slow down postoperative rehabilitation [8,9,10]

  • After adjusting for age, sex, body mass index (BMI), and orthopedic diagnoses using logistic and linear regression analyses, our results showed that tourniquet application remained correlated with a higher transfusion rate (RR = 2.604, 95%confidence interval (CI) 2.075–3.267, P < 0.001) and longer postoperative length of stay (PLOS) (B = 1.294, 95%CI 1.080–1.508, P < 0.001)

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Summary

Objectives

By evaluating the data of 6325 patients, this study aimed to identify the impact of tourniquet use on transfusion rate and PLOS in patients undergoing primary unilateral TKA

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