Abstract
Imprint is a touch preparation in which the cut surface of the tissue is touched gently on a glass slide which leaves behind its impression in the form of cells. Touch imprint cytology is an important diagnostic tool in surgical oncology. It is reliable and economical providing excellent cellular details. The simplicity, speed and cost effectiveness along with the ability to maximize cell recovery even from a tiny tissue makes imprint cytology a valuable resource in diagnostic medicine. Renal tumors have distinct cytological features that facilitate diagnosis on touch imprint cytology. In the present study, correlation of imprint cytology with histopathological diagnosis was done in three cases of renal tumors. DOI: 10.21276/APALM.1268
Highlights
The outcome of any medical care is dependent on rapid and timely diagnosis for the effective management. [1]Touch imprint cytology (TIC) is on the rise in diagnostic cytology because of its main advantage to differentiate between benign and malignant lesions in a shorter time span.[1]
The diagnostic accuracy of TIC is comparable to frozen section with an added advantage of being economical and the access to be done in a low facility set-up.[2,4]Here, we present imprint cytology of renal cell carcinoma and Wilms tumor with histopathological correlation in three cases
Differential diagnosis of Chromophobe renal cell carcinoma (ChRCC) and oncocytoma was given on imprint cytology(Figure 3)
Summary
The outcome of any medical care is dependent on rapid and timely diagnosis for the effective management. [1]Touch imprint cytology (TIC) is on the rise in diagnostic cytology because of its main advantage to differentiate between benign and malignant lesions in a shorter time span.[1]. Individual cells were large round to polygonal having round to oval nuclei with prominent nucleoli and abundant finely granular eosinophilic to vacuolated cytoplasm (Figure 1). Imprint Cytology: Smears were moderately cellular with many atypical cells arranged in monolayered sheets and singly scattered. These cells were round to polygonal with a round to oval eccentric nuclei. Based on these findings, differential diagnosis of ChRCC and oncocytoma was given on imprint cytology(Figure 3). Individual cells were round to polygonal with small round, slightly irregular hyperchromatic nucleus, inconspicuous nucleoli and abundant amount of eosinophilic granular cytoplasm suggestive of ChRCC. Imprint Cytology: High cellular imprint smears showed predominantly blastemal component with cells arranged in small clusters and scattered singly.
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