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https://doi.org/10.1016/s0040-4020(01)89730-1
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Cite Journal: Tetrahedron |  Publication Date: Aug 1, 1991 |
 Citations: 27 |
Affiliation: French National Centre for Scientific Research
The PdCu coupling reaction of a chiral hydroxy-(E,E)-iododiene with a racemic acetylenic alcohol followed by reduction of the dienyne leads to the desired (Z,E,E) geometry and allows synthesis of LTB 4 and its 5-epimer after separation of diastereomers.
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