TOTAL MESORECTUMECTOMY IN THE SURGICAL TREATMENT OF RECTAL CANCER: OPEN OR LAPAROSCOPIC?

Abstract

The OBJECTIVE of the work was to evaluate the long-term results of surgical treatment of patients underwent open and laparoscopic TME for rectal cancer.MATERIAL AND METHODS. The analysis of the results of surgical treatment of 103 patients aged from 20 to 70 years with rectal cancer was presented. Depending on the methods of total mesorectumectomy (ТМЕ), patients were divided into 2 groups. The 1st group included 47 (45.6 %) patients who had underwent laparoscopic total mesorectumectomy (LTME). The 2nd group included 56 patients who had underwent open total mesorectumectomy (OTME). In all patients, the histological structure of the tumor was represented by adenocarcinoma of varying degrees of differentiation. Long-term results of surgical treatment with actual and relapse-free 3-and 5-years survival were observed in 97 (94.2 %) patients.RESULTS. The frequency of local relapses of RC after OTME and LTME was 11.5 % (6 patients) and 11.1 % (5 patients). Distant metastases were detected in 7.7 (4 patients) and 6.7 % (3 patients) of cases, respectively. The actual 3-year survival rate of patients after LTME was 80 %/, 5-year-57.8 %. In patients underwent OTME, these indicators were 81.8 and 54.5 %, respectively.CONCLUSION. A significant correlation was found between the recurrence rate and distant metastases of the RC and the histological structure and degree of tumor differentiation. The differences between the three-year survival rates of patients in both groups are not statistically significant (p>0.05).The authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.