Abstract
Meningioma is the most common intracranial tumor in adults. Often epilepsy is a major clinical manifestation of meningioma. Surgical treatment is a method of choice in patients with meningioma. The early results of the operation and the impact of operations on symptomatic epilepsy are well studied. However, long-term results are poorly investigated.Aim: We were interested in the evaluation of long-term results of surgical treatment of supratentorial meningiomas of the brain and their comparison with the early, as well as the dynamics of symptomatic epilepsy in these patients.Materials and methods: A retrospective analysis of the course of the disease was performed in 110 patients with totally removed supratentorial meningioma of the brain. The long-term results of the effectiveness of surgical treatment are evaluated. The average duration of observation was 48 months (13-83).Results: Neurological deficiency in the preoperative period was observed in 50 patients; at the time of discharge in 40, with an assessment in the distant period - in 12, out of 36 evaluated. Two patients had a hematoma in the removed tumor bed. Postoperative lethality was 1.8% - two patients with vascular complications. 30 of the 40 patients who had epilepsy before the operation became free of attacks after the intervention. In 10 of 40 patients, epilepsy remained. Including 2 patients due to continued growth of meningiomas. In 7 of the 70 patients who did not have attacks before surgery, there were early and / or late postoperative seizures for various reasons. 87 (79%) of tumors were highly differentiated, anaplastic meningioma was detected in 5 (4.5%) patientsConclusions: Total removal of meningiomas can achieve good long-term results. In our series of cases, only 12 (11%) of the neurological deficits with long-term observation were observed in 50 (45.4%) patients who had prior surgery. Symptomatic epilepsy was regressed in 75% of patients. There was an appearance of attacks in 7 patients with 70 patients who had not had an epinephrine before surgery. Histologically, 87 (79%) patients were diagnosed with grade I meningiomas
Highlights
Risk profile associated with convexity meningioma resection in the modern neurosurgical era / Sanai N. et al // Journal of Neurosurgery. 2010
Brain oedema in patients with intracranial meningioma / Lobato R
Summary
Після проведення операції епілептичні напади фіцит спостерігався у 50 (45,4 %) пацієнтів. У 10 зберігалися напади мент виписки неврологічний дефіцит був присутній у віддаленому періоді: 3 мали одиничний напад і в в 40 (36,3 %) пацієнтів. При зборі даних катамнезу вдалося отримати інфор- і регресували після повторного оперативного втрумацію у 36 із 40 пацієнтів, які мали неврологічний чання. Катамнезу чання розвинулися епінапади в подальшому: 1 пазір відновився тільки у 4 пацієнтів з 10, які мали його цієнт мав гострий симптоматичний напад у зв’язку порушення в доопераційному періоді. У 2 (1,8 %) пацієнтів мали місце гематоми через 5 років після операції, без подальших повторів; ложа пухлини, з приводу якої проводилося повторне у 1 пацієнта виникли напади і діагностовано продовоперативне втручання. Детальна клінічна інформація про пацієнтів у яких зберігалися або виникли епілептичні напади після операції наведена в табл. Детальна клінічна інформація про пацієнтів у яких зберігалися або виникли епілептичні напади після операції наведена в табл. 2, 3
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