Abstract
ObjectiveThe objective of this study was to evaluate the surgical, oncologic, and obstetrical outcomes of total laparoscopic radical trachelectomy (LRT) in patients with early-stage squamous cell cervical cancer who want to preserve their fertility. MethodsTwenty-five patients with early-stage cervical cancer were treated by total LRT from January 2005 to December 2012. Data regarding operational time, blood loss, intraoperative-and post-operative complications, recurrence, and subsequent pregnancies were recorded. Other published reports on LRT were also reviewed. ResultsThe median age of the patients was 29years (range 22–34years). The median surgical time was 232min (range, 180–340min). The median blood loss was 120ml (range, 50–200ml), and the median length of hospitalization was 3.3days (range, 2–4days). The median time to return to daily activities was 2days (range, 1–3days). No intra-operative complications occurred; three patients had post-operative complications. The median follow-up time was 66months (range, 1–82months), and no recurrences were observed. Twelve patients attempted to conceive during the follow-up, and nine succeeded. ConclusionsIn this retrospective analysis, total LRT was an effective and safe procedure for patients with early-stage cervical carcinoma who wished to preserve fertility. A larger prospective study with long-term pregnancy and survival analyses is warranted.
Published Version
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