Abstract
Onychomycosis topical treatment is based on several forms of antifungals specialized for nail application. Among them naftifine 1% solution and amorolfine 5% nail lacquer are leading in current use in Russia. These formulations have certain pharmacokinetic properties that may fit various clinical settings in onychomycosis. Early onychomycosis demands prompt recognition and is suitable for application of nail lacquer alone. Rationale for onychomycosis topical treatment is not limited to clinical peculiarities per se. General health condition, comorbidities and their therapy, as well as personal demands of the patient also influence treatment decisions. Efficacy of topical therapy may be limited in onychomycosis with longer history and more severe presentation, where combinations of topical and systemic antifungals may apply. We have conducted pharmacoepidemiological analysis that shows growing demand for amorolfine 5% nail lacquer in Russia. This formulation may be used in prophylactic treatment of onychomycosis, maintaining effective antifungal concentrations in the nail after course of systemic therapy, and for prevention of reinfection from external source.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
