Topical herbal formulation for the treatment of Acne vulgaris

Abstract

Background: Acne vulgaris is the most common bacteria causing chronic inflammatory skin disorder of pilosebaceous unit that affects areas containing the largest oil glands, including the face involving abnormalities in sebum production. Acne vulgaris is characterized by both inflammatory (papules, pustules, and nodules) and no inflammatory (comedones, open and closed) lesions. Acne is a universal disease occurring in all races and affecting 95% of boys and 83% of girls. Methodology: Propionibacterium acnes and Staphylococcus aureus are common pus-forming microbes responsible for the development of various forms of Acne vulgaris and the same organisms were isolated from the human volunteer. This research mainly focuses on the treatment of acne using various herbs and making a poly herbal formulation. The comparative analysis of both solvent and aqueous extraction was done to reveal the fact that the selected ingredient can be used as a poly herbal face care powder for cosmetic purpose. Result: The aqueous and methanolic extraction shows better antibacterial activity against the isolated organisms. Thus in the present work, herbs having good properties for the face care powder formulation have been identified. Conclusion: Natural herbal extracts in combination can be effectively utilized for the treatment of Acne. Use of such products is far better than the use of synthetic ointments for the control of Acne.