To the Analysis of Correlations Between Clinical Manifestations, Postmortem Pathomorphological and Biochemical Changes in Patients with Polytrauma

Abstract

The aim of this work was to establish the relationship between the clinical course of polytrauma in persons who died in medical organizations in a relatively remote posttraumatic period with pathomorphological changes in internal organs and postmortal biochemical shifts. Material and methods. The article presents the results of the analysis of 140 cases of death affected with mechanical trauma in the second and third periods of traumatic disease, including the studying of documented material (original medical card hospital patient, expert archival documents), personal conduct expert studies, holding tanatogenesis analysis, evaluation of results of autopsy, postmortem histological and biochemical studies and their comparison with the clinical data described in the medical records. Results. According to the results of the study, it was found that regardless of the terms of hospitalization in the post-traumatic period exceeding 3 days, the results of various “posthumous” studies (the corpse, its organs, tissues and fluids) actually reflect the final traumatic disease of the corresponding period of hospitalization, are not strictly specific, so often do not allow to speak about a specific nosological unit that led to the development of fatal complications. More such studies provide an opportunity to confirm or deny the presence of the described clinical complications premortal period, to determine the tanatogenesis (mechanism of death) and its compliance with the “picture” of dying. Therefore, information from medical documentation about the clinical course of polytrauma, its manifestations and complications, confirmed by in vivo laboratory methods of research and methods of radiation diagnosis, with their proper expert evaluation, are of fundamental diagnostic importance for the scientifically grounded and objective establishment of the main (original) cause of death, developed tanatogenetically significant complications and their relationship with the injury.