Abstract
The study was performed at the Department of Pharmacology in collaboration with Department of Psychiatry, NSCB Medical College, Jabalpur. The maximum numbers of patients in were in reproductive age group that is in between 20 to 49 years. The mean age in Amisulpride group was 33.26(±10.23) years while in Olanzapine group it was 31.25 (±12.22) years.
 Schizophrenia was more common (80%) in younger (20-49years) age group. In our study the male /female ratio was 1.7. Our study supports the notion that Schizophrenia is more common in Married and Urban population. Only one patient from Olanzapine Group suffered Extrapyramidal symptoms of moderate severity requiring withdrawal from study.2 patients from Olanzapine group and 1 patient from Amisulpride group had Tremors and Akathesia of mild severity. There was no emergence of Extrapyramidal symptoms in rest of the patients (p>.05)
 Keywords: Efficacy, Amisulpride, Olanzapine & Schizophrenia.
Highlights
Schizophrenia is the term for a group of disorders marked by chronicity, impaired behavioral function, and disturbances of thinking and affect.[1]Eugene Bleuler (1857 to 1939) was a Swiss psychiatrist generally credited for coining the term schizophrenia, of which he described primary symptoms of abnormal associations, abnormal affect, autistic behavior, and ambivalence the four A’s.Schizophrenia is a severe mental disorder which accounts for much suffering of those affected and their families, in addition to a cost to society estimated as 1.1% of the total burden of disease and 2.8% of the total YLDs (Mental health policy and service development)2 & 3Life expectancy is decreased as compared to the general population, due to suicide but in particular due to cardiovascular disease
The maximum number of patients in was in reproductive age group that is in between 20 to 49 years
No of Patients Lost to Follow up No of Patients Lost due to Adverse Effects: AMISULPIRIDE 7
Summary
Schizophrenia is the term for a group of disorders marked by chronicity, impaired behavioral function, and disturbances of thinking and affect.[1]Eugene Bleuler (1857 to 1939) was a Swiss psychiatrist generally credited for coining the term schizophrenia, of which he described primary symptoms of abnormal associations, abnormal affect, autistic behavior, and ambivalence the four A’s.Schizophrenia is a severe mental disorder which accounts for much suffering of those affected and their families, in addition to a cost to society estimated as 1.1% of the total burden of disease (in terms of DALYs –disability adjusted life-years) and 2.8% of the total YLDs (years lived with disability) (Mental health policy and service development)2 & 3Life expectancy is decreased as compared to the general population, due to suicide but in particular due to cardiovascular disease. Schizophrenia is the term for a group of disorders marked by chronicity, impaired behavioral function, and disturbances of thinking and affect.[1]. Eugene Bleuler (1857 to 1939) was a Swiss psychiatrist generally credited for coining the term schizophrenia, of which he described primary symptoms of abnormal associations, abnormal affect, autistic behavior, and ambivalence the four A’s. Schizophrenia is a severe mental disorder which accounts for much suffering of those affected and their families, in addition to a cost to society estimated as 1.1% of the total burden of disease (in terms of DALYs –disability adjusted life-years) and 2.8% of the total YLDs (years lived with disability) (Mental health policy and service development)2 & 3. Life expectancy is decreased as compared to the general population, due to suicide but in particular due to cardiovascular disease
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