Abstract
Response to: A Commentary on "Antipsychotic-Induced Parkinsonism is Associated with Working Memory Deficits in Schizophrenia-Spectrum Disorders".
Highlights
A commentary on “Antipsychotic-induced parkinsonism is associated with working memory deficits in schizophrenia-spectrum disorders” by Salem, A. and Moustafa, A
We read with interest the commentary from Drs Salem and Moustafa (2015) on our paper and we would like to take the opportunity to further discuss two issues, namely, the use of chlorpromazine equivalents (CPZs) to control for the effects of antipsychotics and the need for longitudinal studies examining the complex relationships between cognition and antipsychotic-induced extrapyramidal symptoms (EPS) in schizophrenia
The second issue that we wanted to raise concerns the fact that most studies investigating the relationship between cognition and EPS in schizophrenia are based on cross-sectional designs, which are more vulnerable to confounding factors than longitudinal designs
Summary
A commentary on “Antipsychotic-induced parkinsonism is associated with working memory deficits in schizophrenia-spectrum disorders” by Salem, A. and Moustafa, A. We read with interest the commentary from Drs Salem and Moustafa (2015) on our paper and we would like to take the opportunity to further discuss two issues, namely, the use of chlorpromazine equivalents (CPZs) to control for the effects of antipsychotics and the need for longitudinal studies examining the complex relationships between cognition and antipsychotic-induced extrapyramidal symptoms (EPS) in schizophrenia.
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