Abstract
Aim: The effect of intra-lesional corticosteroids in management of patients with OSMF.
 Materials and Methods: The present clinic-observational study was conducted among 100 diagnosed patients of OSMF who attended the OPD of Nalanda Medical College and Hospital Patna, Bihar, India. The collected data were subjected to statistical analysis using SPSS version 20 software.
 Results: Mean age of the study population was 29.12 years. Study shows a definite male predominance (74%). Statistical analysis revealed that there was a significant improvement in the mouth opening and VAS.
 Conclusion: The present study concluded that dexamethasone (2 ml Decadron 4 mg/ml) injection and hyaluronidase 1500 IU with 2% lignocaine was administered, and there was significant improvement in mouth opening and VAS.
 Keywords: Dexamethason, Mouth Opening, OSMF, VAS
Highlights
Oral submucous fibrosis (OSMF) has been mentioned in the Indian medical literature, since the time of ‘Sushruta’ ‟who named it as ‘Vidari’
The present study concluded that dexamethasone (2 ml Decadron 4 mg/ml) injection and hyaluronidase 1500 IU with 2% lignocaine was administered, and there was significant improvement in mouth opening and Visual Analogue Scale (VAS)
Study Design, Population, Setting The present clinic-observational study was conducted among 100 diagnosed patients of OSMF who attended the OPD of Nalanda Medical College and Hospital, Patna, Bihar
Summary
Oral submucous fibrosis (OSMF) has been mentioned in the Indian medical literature, since the time of ‘Sushruta’ ‟who named it as ‘Vidari’. The disease was first reported in 1952 by Schwartz to which he ascribed the descriptive term ‘Atrophica idiopathica (tropica) mucosa oris’ and its precancerous nature was reported by ‘Paymaster’ in 1956. The WHO definition for an oral precancerous condition was stated as: ‘A generalized pathological state of the oral mucosa associated with a significantly increased risk of cancer. Later on in 2007 Warnakulasuriya et al termed OSMF as a potentially malignant disorder. Intra-lesional corticosteroids in management of patients with OSMF
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