TLR6 Gene Polymorphism, Sequence Analysis, and Phylogenetic Tree in Susscrofa

Abstract

TLRs (Toll like receptors) gene have a very important role in early defense against invading pathogens, still we do not have sufficient literature available about them specially TLR6 gene in swine. The current study deals with the characteristic polymorphic, sequencing and evolutionary pattern of TLR6 gene in swine. SSCP based amplification and polymorphic pattern of TLR6 gene, with the eight primers showed different polymorphism. Further, the evolutionary pattern of TLR6 gene was studied through phylogenetic tree analysis. Conclusively, the current comparative phylogenetic and polymorphic analysis of vertebrate TLR6 gene in swine provided informative insights into the process of gene evolution.