Titanium(III) Chloride-Lithium Aluminum Hydride

Abstract

(TiCl3) [7705-07-9] Cl3Ti (MW 154.23) InChI = 1S/3ClH.Ti/h3*1H;/q;;;+3/p-3 InChIKey = YONPGGFAJWQGJC-UHFFFAOYSA-K (LiAlH4) [16853-85-3] AlH4Li (MW 37.96) InChI = 1S/Al.Li.4H/q-1;+1;;;; InChIKey = OCZDCIYGECBNKL-UHFFFAOYSA-N (reagent combination for the production of low-valent titanium which is used for the inter- and intramolecular reductive coupling of carbonyl and dicarbonyl compounds, as well as reductive elimination reactions) Physical Data: see Titanium(III) Chloride and Lithium Aluminum Hydride. Solubility: THF and DME are the favored solvents for reactions involving low-valent titanium. Form Supplied in: a 4∶1 ball-milled mixture of TiCl3 and LiAlH4 is available, which serves as a precursor to the McMurry reagent. Handling, Storage, and Precautions: most commonly, low-valent titanium species are prepared, under an inert atmosphere (nitrogen or argon), immediately prior to use. Presumably the reagent is pyrophoric, although this property may be due to the residual reducing agent used in the preparation process rather than an inherent property of Ti0/TiI itself. The reagent is moisture sensitive.