Abstract
In this study, the vertically aligned titania nanotube arrays (TNTs) was fabricated on the surface of titanium substrate in fluoride-containing electrolytes via self-ordering electrochemical anodization. The prepared TNTs loaded with ibuprofen (IBU) by solvothermal to achieve a local drug delivery system and its release properties were investigated. The samples were characterized by field emission scanning electronic microscope (FE-SEM), X-ray diffraction (XRD), Fourier transform infrared (FT-IR). The results indicated that the IBU drug molecules were successfully loaded on the surface of TNTs and the drug release shows a sustained release process. It suggested that TNTs as drug carrier had the properties of sustained release which have a good application prospect in biomedical field.
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