Abstract
This is a Photo Essay and does not have an abstract. Please download the PDF or view the article HTML.
Highlights
A 76-year-old female presented with a history of non-exudative macular degeneration presented with a submacular hemorrhage (SMH) due to conversion to exudative macular degeneration in the left eye [Figure 1]
Mild toxicity results in localized outer retinal dysfunction in rabbits, while severe toxicity can result in extensive retinal necrosis.[2]
Chen et al described the case of a 49-year-old male who developed tissue plasminogen activator (tPA)-induced retinal pigment epithelium (RPE) changes within five weeks after two 50 μg injections of tPA for SMH into the vitreous cavity
Summary
A 76-year-old female presented with a history of non-exudative macular degeneration presented with a submacular hemorrhage (SMH) due to conversion to exudative macular degeneration in the left eye [Figure 1]. Subretinal tPA to treat SMH is increasingly used due to its generally excellent outcomes.[1] tPA can induce retinal toxicity in a dose dependent manner.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call