Abstract
Tissue cultures have been used as laboratory model systems to inquire into problems in neurobiogenesis, neurotoxicology, neural-viral inter-relationships and the demyelinating disorders. This short article will present, in a simplified manner, the way in which the myelinated cultures of mammalian CNS and peripheral nervous system tissues have contributed to our understanding of the demyelinating disorders and led to a clinical trial to evaluate the possibility that a particular polypeptide may offer an effective means of altering the course of multiple sclerosis.
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