Timing of cholecystectomy in patients with mild biliary acute pancreatitis

Abstract

Objective To investigate the timing of cholecystectomy in patients with mild biliary acute pancreatitis. Methods 80 patients with mild acute biliary pancreatitis were prospectively collected. According to the principle of random digital table, the patients were randomly divided into the study group and control group, 40 cases in each group. The study group underwent early cholecystectomy, while the control group received delayed cholecystectomy. Main indicators included biliary tract complications, perioperative complications, conversion to open surgery, operation time and total hospital stay were observed. Results Compared with the control group, the total hospitalization time of the study group was significantly shorter[(9.39±2.48)d vs. (11.48±3.28)d, t=3.582, P=0.000]. There were no statistically significant differences in the rate of conversion to open surgery, operation time, perioperative complications and mortality between the two groups (P>0.05). The incidence rates of acute cholecystitis, biliary colic and total biliary complications of the study group were 0.00%, 0.00% and 0.00%, which were significantly lower than those in the control group (15.00%, 22.50% and 47.50%) (χ2=4.505, 8.013 and 22.364, P=0.034, 0.005 and 0.000). Conclusion Early laparoscopic cholecystectomy is helpful to reduce the incidence of adverse events in the biliary system. Key words: Pancreatitis; Gallstones; Cholecystectomy