Abstract
In view of same time delay τ in active and passive transport processes of intracellular Ca2+ with additive Gaussian colored noise, using second-order algorithm for stochastic simulation colored noise, intracellular calcium oscillation (ICO) is investigated. By researching the time series and stationary probability distribution (SPD) of intracellular Ca2+ concentrations, take modest strength and enough long correlation time of additive colored noise, the results indicate that: time delay has a critical point τc ≃ 0.1s of time coherence, as τ > τc, ICO become periodical oscillation, and the waveform converts slowly into square wave from saw-tooth calcium wave as time delay further increases. Additionally, ICO system appears transition from monostable state to bistable state as time delay increases.
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