Time-course RNA-Seq analysis defines immunological and inflammatory mechanisms influenced by bovine respiratory disease

Abstract

Bovine respiratory disease (BRD) remains the leading disease in beef cattle. Host gene expression at facility arrival may indi­cate BRD risk, however, time-course RNA-Seq could define how BRD development influences immunological and inflammatory responses. Here, we evaluated blood transcriptomes of high-risk beef cattle at 3 timepoints to illustrate BRD-associated host response.