Abstract
Low temperature plasma jets gained increased interest in the last years as a potential device in many life science applications, including here human or veterinary medicine. Standardisation of plasma sources and biological protocols are necessary for quality assurance reasons, due to the fact that this type of atmospheric pressure plasma source is available in multiple configurations and their operational parameters span also on a broad range of items, such as all characteristics of high voltage pulses used for gas breakdown, geometrical characteristics, gas feed composition and conductive or biological target characteristics. In this paper we present results related to electrical, optical and molecular beam mass spectrometry diagnosis of a helium plasma jet, emphasising the influence of various operational parameters of the high voltage pulses on plasma jet properties. Discussion on physical parameters that influence the biological response is included, together with important results on plasma sources statistical behaviour until reaching a quasi-stationary working regime. The warm-up period of the plasma jet, specific to many other plasma sources, must be precisely known and specified whenever the plasma jets are used as a tool for life science applications.
Highlights
Atmospheric pressure plasmas based devices are suitable solutions to generate transient or stationary plasmas, with various applications
This paper aims to present fundamental aspects related to the physics of atmospheric pressure helium plasma jet, generated using the barrier discharge principle
The negative current peak, characteristic to dielectric barrier discharges, is associated with a discharge event generated only in the spatial region delimited by dielectrics, that can accumulate charge during first phase on discharge and produce an internal field inversion during falling edge of high voltage (HV) pulses
Summary
Atmospheric pressure plasmas based devices are suitable solutions to generate transient or stationary plasmas, with various applications. Over the past half-century, atmospheric pressure plasma jets (APPJ) were widely used for technological applications, starting with thermal plasma jets used for propulsion, cutting and welding devices or materials deposition [1]. Non-thermal plasma jets were developed in various configurations, as response to the increasing industry demands to process heat sensitive materials. This opened the possibility to accurately study the plasma jets facing natural biological architectures or living organisms. These are unique natural molecular structures, presenting a hierarchical organization with many levels, able to respond to external stimuli, to self-repair and to replace damaged molecules or sub-assemblies, often showing an increasing resistance to various forms
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