Abstract
Tickborne Meningoencephalitis, First Case after 19 Years in Northeastern Germany
Highlights
To the Editor: Tickborne encephalitis virus (TBEV) is focally distributed in Europe and Asia
IgG and IgM antibodies were positive in serum and cerebrospinal fluid (CSF), while CSF leukocyte count and protein concentration were normal
Even though CSF specimens were negative for TBEV genome on 2 occasions, a confirmed tickborne encephalitis case had to be reported to the health authorities
Summary
To the Editor: Tickborne encephalitis virus (TBEV) is focally distributed in Europe and Asia (between 42° and 63° north latitude). A 61-year-old man was bitten by a tick at Lake Woblitz, near the town of Neustrelitz in former East Germany, on May 31, 2004, between 8:00 a.m. and 4:00 p.m. The patient’s history showed no other tick bites, no stays in tickborne encephalitis–endemic areas, and no tickborne encephalitis vaccination. Tests on CSF showed mild pleocytosis (9 leukocytes/μL) and high protein concentration (1,322 g/L). IgG and IgM antibodies were detectable in the serum by enzymelinked immunosorbent assay 29 days after the tick bite; corresponding CSF titers were borderline.
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