Abstract

Background: Polycystic ovarian syndrome (PCOS) is the most common form of chronic anovulation associated with androgen excess; perhaps occurring in 5-10% of reproductive women. 
 Methods: Observational study done in the Department of Obstetrics & Gynaecology, SMS Medical College, Jaipur. Forty cases of women with PCOS based on Rotterdam’s criteria and an equal number of age-matched controls (women without PCOS) were included in the study.
 Results: T4 level was significantly lower in PCOS group with mean free T4 level 0.87 ± 0.75 ng/ml in PCOS group v/s 1.92 ± 0.84 ng/ml in control group (p-value = 0.001). TSH level was significantly higher in PCOS group with mean TSH level 8.86 ± 7.57 mU/L in PCOS group v/s 3.40 ± 1.21 mU/L in control group (p-value = 0.001)
 Conclusion: High prevalence of thyroid disorders in PCOS patients thus points towards the importance of early correction of hypothyroidism in the management of infertility associated with PCOS.
 Keywords: T4, T3, TSH, PCOS

Highlights

  • Polycystic ovarian syndrome (PCOS) is the most common form of chronic anovulation associated with androgen excess; perhaps occurring in 5-10% of reproductive women

  • T4 level was significantly lower in PCOS group with mean free T4 level 0.87 ± 0.75 ng/ml in PCOS group v/s 1.92 ± 0.84 ng/ml in control group (p-value = 0.001)

  • TSH level was significantly higher in PCOS group with mean TSH level 8.86 ± 7.57 mU/L in PCOS group v/s 3.40 ± 1.21 mU/L in control group (p-value = 0.001) Conclusion: High prevalence of thyroid disorders in PCOS patients points towards the importance of early correction of hypothyroidism in the management of infertility associated with PCOS

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Summary

Introduction

Abstract Background: Polycystic ovarian syndrome (PCOS) is the most common form of chronic anovulation associated with androgen excess; perhaps occurring in 5-10% of reproductive women. Methods: Observational study done in the Department of Obstetrics & Gynaecology, SMS Medical College, Jaipur. Forty cases of women with PCOS based on Rotterdam’s criteria and an equal number of age-matched controls (women without PCOS) were included in the study.

Results
Conclusion
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