Estimation of Serum AdiponectinIrisin and Apelin in Iraqi Obese Women Patients with Polycystic Ovary Syndrome

Abstract

Polycystic ovary syndrome (PCOS) is a status that impact a woman’s hormone levels.A total of (128) samples was divided into four groups (Obese with PCOS, low weight with PCOS ,Obese without PCOS ,and Healthy control) collected from Kamal Al-Samarraiehospital, Ministry-of Health in Baghdad-Iraq during the period of April 2017- August 2017. The aim of the study toevaluation from Serum AdiponectinIrisin and Apelin in Iraqi obese women patients with PCOS. The result shows The BMI of obese with PCOS patients and obese without PCOS was significantly higher (P<0.05) when compared to the values of the control group. No significant with other groups ,also Significant increase of Prolactin (p<0.05) in Obese with PCOS and low weight with PCOS groups in relation to Obese without PCOS and control groups. A non- significant elevation (p>0.05)when comparing between Obese without PCOS, and control groups. The levels of FSH , LH and Testosterone showed significantly change(p<0.05) in Obese with PCOS and low weight with PCOS groups when comparing with Obese without PCOS and control group. followed by no-significant with other groups ,also shows significant change(p<0.05)when comparing between Obese without PCOS and control group ,showed that adiponectin level showed a significant higher level in the control group ,Obese without PCOS group ,low weight with PCOS patients ,and Obese with PCOS patients . Oppositely, the results of the Irisin showed a significant higher level in the Obese with PCOS patients then the low weight with PCOS group followed by the Obese without PCOS and control group. While Apelin level recorded the highest level Obese with PCOS group.