Abstract
Objective To investigate the nursing effects of Thymosin α1 for injection dilution (Zadaxin dilution) on the patients with oral ulcers caused by oral endotracheal intubation. Methods One hundred patients with oral ulcers caused by oral endotracheal intubation in the ICU of the Second Affiliated Hospital of Wenzhou Medical University from May 2014 to September 2015 were randomly divided into the observation group(n=50) and the control group(n=50)according to random number table. For the oral care, the patients with oral ulcers were treated with Thymosin α1 for injection dilution and compound chlorhexidine gargle in the observation group and the control group respectively. Therapeutic effects and ulcer healing time were observed and compared between the two groups. Results The clinical therapeutic effects in the observation group was significantly better than that in the control group (P<0.05). The healing time in the observation group was significantly shorter than that in the control group (P<0.05). Conclusions Thymosin α1 for injection dilution has a better effects than compound chlorhexidine gargle on the treatment of oral ulcers in the patients with oral endotracheal intubation. Thymosin α1 for injection dilution is worthy of clinical promotion. Key words: Nursing care; Oral ulcer; Intubation, intratracheal; Thymosin α1 for injection dilution
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