Abstract

SUMMARY: Growing Escherichia ccli wild-type and pyrimidine-deficient strains break down exogenously added pyrimidine bases, thymine and uracil, whose 2-carbon atom appears as CO2. By using mineral salts glucose media with different sources of nitrogen the degradation processes are shown to be inducible. We conclude that thymine and uracil catabolism are regulated by the amount of metabolically available nitrogen in the ce|l.

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