THU0614 FINGER EXTENSOR TENDON INVOLVEMENT IS FREQUENT IN EARLY RHEUMATOID ARTHRITIS

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Background: Finger extensor tendon (FET) involvement at ultrasound examination (US) was previously described in patients suffering from early and established psoriatic arthritis1. The reliability of the US measure of FET was as least as good as for synovitis2. The involvement of the FET in patients suffering from rheumatoid arthritis remains controversial. Objectives: To assess the involvement of FET in early rheumatoid arthritis (ERA) patients and in asymptomatic subjects (CTR). Methods: Inclusion criteria for ERA patients were: less than 6 months since the ERA diagnosis; age >18 years; without DMARD treatment or oral glucorticoid treatment. Inclusion criteria for CTRL subjects were : age >18 years; no pain in hands and fingers (VAS pain =0/100); no known rheumatic disease such a systemic diseases, rheumatoid, psoriatic arthritis, spondyloarthritis, hand osteoarthritis, gout, chondrocalcinosis; no psoriasis, no inflammatory bowel diseases. US assessments were performed blindly to the clinical and laboratory data. FET were assessed in longitudinal and in transverse view at the metacarpo phalangeal joint (MCP) and proximal phalangeal joint (PIP) level both in grey-scale (GS), power Doppler (PD) and in color Doppler (CD) mode. In addition the following joints were assessed for the presence and grade (0-3 according to OMERACT definitions) for both GS and PD synovitis: wrists, ankles, metatarsophalangeal (MTP) (2-5) and MCP (1-5) joints. Results: Sixty-two consecutive ERA patients and 34 CTR were included in this study. Mean age and gender distribution were comparable between ERA and CTR (47,3±14,5 vs. 43,4±12,5). ACPA were present in 61%, rheumatoid factor in 54%, and bone erosions in 27% of ERA patients. 57% of ERA patients presented with FET and 0% of CTR (p Conclusion: FET is relatively frequent in ERA patients and it is not present in asymptomatic subjects. Our results show that FET involvement is associated with the presence of ACPA, rheumatoid factor and bone erosions, thus identifying patients with possibly more aggressive or severe disease at baseline.