THU0509 Improvement of disease activity in patients with colchicine-resistant FMF, HIDS/MKD and traps assessed by autoinflammatory disease activity index (AIDAI): results from the cluster trial

Isabelle Koné‐Paut ,Seza Özen ,J B Kuemmerle‐Deschner ,Jérémy Levy ,Marco Gattorno ,Michaël Hofer ,Maryam Piram ,Cs Karyekar ,Joost Frenkel ,Helen Lachmann ,Susanne M Benseler ,Hm Hoffman ,Fabrizio Benedetti

doi:10.1136/annrheumdis-2017-eular.5655

THU0509 Improvement of disease activity in patients with colchicine-resistant FMF, HIDS/MKD and traps assessed by autoinflammatory disease activity index (AIDAI): results from the cluster trial

Isabelle Koné‐Paut , Seza Özen + Show 11 more

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Journal: Annals of the Rheumatic Diseases	Publication Date: Jun 1, 2017
Citations: 3

Affiliation: Bicêtre Hospital, Hacettepe University, Istituto Giannina Gaslini, University of Lausanne, Tris Pharma (United States), University Medical Center Utrecht, Alberta Children's Hospital, University of California, San Diego, Bambino Gesù Children's Hospital

#TNF Receptor-associated Periodic Syndrome #Serum Amyloid A #Physician Global Assessment #Colchicine Resistant Familial Mediterranean Fever #SF12 MCS #Proportion Of Pts #Ann Rheum Dis #C-reactive Protein #Inactive Disease #Child Health Questionnaire

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BackgroundAIDAI is a novel validated tool for assessment of disease activity in autoinflammatory diseases.1 CLUSTER study (NCT02059291) demonstrated that canakinumab (CAN; an anti- IL-1β antibody) is efficacious in resolving active...

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THU0509 Improvement of disease activity in patients with colchicine-resistant FMF, HIDS/MKD and traps assessed by autoinflammatory disease activity index (AIDAI): results from the cluster trial