THU0107 CCL19, a chemokine involved in B-cell trafficking, is related to the decrease of blood memory B-cells and predicts the clinical response to rituximab in rheumatoid arthritis: Results from the smart study

J Sellam,H Hendel-Chavez,S Rouanet,X Mariette,Y Taoufik,J Sibilia,B Combe,X Le Loët,K Abbed,R Jourdan,M Dougados,J Tebib

doi:10.1136/annrheumdis-2012-eular.2072

THU0107 CCL19, a chemokine involved in B-cell trafficking, is related to the decrease of blood memory B-cells and predicts the clinical response to rituximab in rheumatoid arthritis: Results from the smart study

J Sellam, H Hendel-Chavez + Show 10 more

https://doi.org/10.1136/annrheumdis-2012-eular.2072

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Journal: Annals of the Rheumatic Diseases

Publication Date: Jun 1, 2013

Affiliation: Sorbonne Université, University of Paris-Sud, Bicêtre Hospital, Roche (France), Inserm, Hôpitaux Universitaires de Strasbourg, University of Strasbourg, University Hospital of Montpellier, Délégation Paris 5

#Roche France #B-cell Trafficking + Show 8 more

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BackgroundIn rheumatoid arthritis (RA), the decrease of peripheral blood memory B-cell may be explained by their migration into the synovium and predicts the response to rituximab (RTX), delineating thus a...

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