ThTP7.11 Comparison of oncological outcomes of patients having colorectal surgeries: During lockdown vs post lockdown

Abstract

Abstract Aims When the UK entered the lockdown, the cancer pathways changed to deal with the pandemic and protect cancer patients from infection. The objective of our study is to compare the oncological outcomes of patients having surgery for colorectal cancer (CRC) during and after lockdown. Methods Patients who underwent surgery for CRC between March-2020 to February-2022 were included in the study. All patient related and disease specific details were collected from the prospectively maintained database. Patients were divided in to two groups: Surgeries before (group-A: during lockdown) and after 22/2/21 (group-B: after lockdown). Patient demographics such as age, tumour and nodal staging, and survival outcome was calculated. Log-rank test and Kaplan-meir survival curve was used to analyse the survival outcome. Results A total of 450 patients underwent surgeries during this period, of which 358 had cancer resections. During lockdown 171 patients had cancer resections (Group-A) and 187 patients had surgery for cancer after lockdown (Group-B). The median age of patients is 72 and 73 years in group-A and B respectively(p-value:0.29). There is no difference between the two groups with respect to tumour and nodal staging. In group-A, 13 patients had recurrence and 26 died due to disease with a median follow up of 23 months. In group-B, 22 patients had recurrence and 18 died due to disease with a median follow up of 13 months (p-value:0.42 log rank test). Conclusions The patients undergoing treatment of CRC during lockdown had similar oncological outcomes compared with patients having treatment after the lockdown.